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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CKMT1A All Species: 34.85
Human Site: Y47 Identified Species: 58.97
UniProt: P12532 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P12532 NP_001015001.1 417 47037 Y47 A S E R R R L Y P P S A E Y P
Chimpanzee Pan troglodytes XP_517671 356 40461 T30 T L D Q C I Q T G V D N P G H
Rhesus Macaque Macaca mulatta XP_001102013 767 82902 Y397 A S E R R R L Y P P S A E Y P
Dog Lupus familis XP_535451 417 47057 Y47 A S E R R R L Y P P S A E Y P
Cat Felis silvestris
Mouse Mus musculus P30275 418 46985 Y48 A A E R R R L Y P P S A E Y P
Rat Rattus norvegicus P25809 418 47010 Y48 T G E R R R L Y P P S A E Y P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516190 602 66708 Y47 A G D R R R L Y P P S A E Y P
Chicken Gallus gallus P70079 417 47085 Y47 G E R Q R R R Y P P S A E Y P
Frog Xenopus laevis NP_001080463 418 46838 Y48 T S H K R R M Y P A S A E Y P
Zebra Danio Brachydanio rerio XP_002663507 417 46785 Y47 A D E K R K L Y P P S A D F P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48610 356 39848 L30 K S L L K K Y L T K E V F D N
Honey Bee Apis mellifera O61367 355 39990 Y29 S K S L L K K Y L S K D V F D
Nematode Worm Caenorhab. elegans Q10454 396 44149 E49 P D V I A K I E E G Y A K L Q
Sea Urchin Strong. purpuratus P18294 1174 130851 K802 C R P K P P I K P F S Y D Y P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.1 54.2 98.3 N.A. 96.6 95.9 N.A. 65.2 88.4 83 79.8 N.A. 37.8 37.4 38.6 24.4
Protein Similarity: 100 78.6 54.3 99.2 N.A. 98.3 97.8 N.A. 68.1 93 91.1 90.4 N.A. 54.9 55.1 53.7 30
P-Site Identity: 100 0 100 100 N.A. 93.3 86.6 N.A. 86.6 66.6 66.6 66.6 N.A. 6.6 6.6 6.6 26.6
P-Site Similarity: 100 13.3 100 100 N.A. 100 86.6 N.A. 93.3 73.3 80 93.3 N.A. 20 26.6 26.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 43 8 0 0 8 0 0 0 0 8 0 72 0 0 0 % A
% Cys: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 15 0 0 0 0 0 0 0 8 8 15 8 8 % D
% Glu: 0 8 43 0 0 0 0 8 8 0 8 0 58 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 8 15 0 % F
% Gly: 8 15 0 0 0 0 0 0 8 8 0 0 0 8 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 8 0 8 15 0 0 0 0 0 0 0 0 % I
% Lys: 8 8 0 22 8 29 8 8 0 8 8 0 8 0 0 % K
% Leu: 0 8 8 15 8 0 50 8 8 0 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % N
% Pro: 8 0 8 0 8 8 0 0 72 58 0 0 8 0 72 % P
% Gln: 0 0 0 15 0 0 8 0 0 0 0 0 0 0 8 % Q
% Arg: 0 8 8 43 65 58 8 0 0 0 0 0 0 0 0 % R
% Ser: 8 36 8 0 0 0 0 0 0 8 72 0 0 0 0 % S
% Thr: 22 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % T
% Val: 0 0 8 0 0 0 0 0 0 8 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 72 0 0 8 8 0 65 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _